Details for gene set NCI_IL12-MEDIATED SIGNALING EVENTS[GSEA]

Table: GSEA Results Summary

Dataset	Set_03_truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy_repos
Phenotype	phenotype_truncNotch_versus_normalThy.cls#truncNotch_versus_normalThy_repos
Upregulated in class	normalThy
GeneSet	NCI_IL12-MEDIATED SIGNALING EVENTS
Enrichment Score (ES)	-0.60101175
Normalized Enrichment Score (NES)	-1.491603
Nominal p-value	0.0053333333
FDR q-value	0.37204397
FWER p-Value	0.998

Table: GSEA details [plain text format]
	PROBE	DESCRIPTION (from dataset)	RANK IN GENE LIST	RANK METRIC SCORE	RUNNING ES	CORE ENRICHMENT
1	ETV5	110017	222	1.935	0.0306	No
2	IL2RA	6620450	647	1.126	0.0325	No
3	STAT5A	2680458	724	1.049	0.0515	No
4	CCL4	50368 430047	1111	0.774	0.0477	No
5	IL12RB1	2230338 5420053	1150	0.749	0.0621	No
6	ARRB2	2060441	1293	0.658	0.0689	No
7	IL27RA	940093	1594	0.529	0.0644	No
8	TGFB1	1940162	1706	0.484	0.0690	No
9	STAT6	1190010 5720019	1834	0.444	0.0720	No
10	IL12RB2	6020465	1910	0.425	0.0773	No
11	NFKB1	5420358	1928	0.422	0.0856	No
12	TYK2	1660465 1740736	1953	0.413	0.0934	No
13	CD80	870112	2013	0.392	0.0988	No
14	TBX21	5270594	2254	0.330	0.0931	No
15	IRF1	2340152 3450592 6290121 6980577	2547	0.253	0.0829	No
16	PRF1	6660309	2711	0.213	0.0788	No
17	IL2RB	4730072	2982	0.168	0.0680	No
18	CCL3	2810092	2985	0.168	0.0715	No
19	BCL3	3990440	3203	0.139	0.0629	No
20	GADD45G	2510142	3283	0.130	0.0615	No
21	PRKCA	6400551	3576	0.103	0.0479	No
22	IL13	7040021	4284	0.063	0.0111	No
23	IL1R1	3850377 6180128	4407	0.058	0.0058	No
24	PIAS2	1690301 5900647	4753	0.048	-0.0118	No
25	EBI3	5340300	4842	0.045	-0.0155	No
26	IL4	6020537	5032	0.041	-0.0248	No
27	GZMA	3390315	5179	0.038	-0.0319	No
28	FRAP1	2850037 6660010	5731	0.028	-0.0611	No
29	JAK2	3780528 6100692 6550577	6101	0.022	-0.0805	No
30	IL17A	4280369	6831	0.016	-0.1195	No
31	IL12B	460008	6924	0.015	-0.1242	No
32	PIK3R1	4730671	7321	0.013	-0.1453	No
33	FOS	1850315	7390	0.012	-0.1487	No
34	REL	360707	8673	0.007	-0.2178	No
35	CCR5	1980072 5910722	8890	0.006	-0.2293	No
36	IL27	1990324	9004	0.005	-0.2353	No
37	RAN	2260446 4590647	9367	0.004	-0.2548	No
38	XPO1	540707	9449	0.004	-0.2590	No
39	IL18	6180039	9510	0.004	-0.2622	No
40	IL2	1770725	9837	0.003	-0.2797	No
41	B2M	5080332 5130059	10512	0.001	-0.3161	No
42	ATM	3610110 4050524	10891	0.000	-0.3365	No
43	GZMB	380066	11345	-0.001	-0.3610	No
44	IL12A	7100551	11444	-0.002	-0.3662	No
45	MAP2K3	5570193	11950	-0.003	-0.3934	No
46	TNF	6650603	12391	-0.005	-0.4171	No
47	IL18RAP	3850088	12831	-0.007	-0.4406	No
48	IFNG	5670592	12891	-0.007	-0.4437	No
49	FBXW11	6450632	13100	-0.009	-0.4547	No
50	EOMES	2100707	13226	-0.010	-0.4612	No
51	SRC	580132	13235	-0.010	-0.4615	No
52	IL1B	2640364	13266	-0.010	-0.4629	No
53	IL6	380133	13456	-0.012	-0.4728	No
54	SYK	6940133	13689	-0.014	-0.4850	No
55	STAT4	1660373 3130019	13798	-0.016	-0.4905	No
56	JUN	840170	13846	-0.016	-0.4927	No
57	PIK3CA	6220129	13861	-0.016	-0.4931	No
58	ERC1	1580170 2630717 6110762 6840280	14397	-0.028	-0.5214	No
59	NOD2	2510050	14872	-0.050	-0.5459	No
60	MALT1	4670292	14919	-0.053	-0.5472	No
61	FASLG	2810044	15163	-0.069	-0.5588	No
62	RELB	1400048	15248	-0.075	-0.5617	No
63	IL18R1	270546	15330	-0.083	-0.5642	No
64	IKBKG	3450092 3840377 6590592	15397	-0.091	-0.5658	No
65	JAK1	5910746	15408	-0.091	-0.5643	No
66	BIRC2	2940435 4730020	15427	-0.093	-0.5633	No
67	NFKB2	2320670	15588	-0.110	-0.5695	No
68	CD86	3390471 6200280	15640	-0.116	-0.5697	No
69	GADD45B	2350408	15818	-0.136	-0.5762	No
70	UBE2D3	3190452	15912	-0.149	-0.5780	No
71	RAB7A	450433 4070112 4480324	16069	-0.173	-0.5826	No
72	ATF2	2260348 2480441	16133	-0.183	-0.5820	No
73	RIPK2	5050072 6290632	16153	-0.187	-0.5789	No
74	MAPK8	2640195	16564	-0.281	-0.5948	Yes
75	IKBKB	6840072	16617	-0.298	-0.5911	Yes
76	LCK	3360142	16671	-0.311	-0.5871	Yes
77	RELA	3830075	16834	-0.358	-0.5879	Yes
78	CD3D	2810739	16975	-0.406	-0.5866	Yes
79	CREBBP	5690035 7040050	17020	-0.421	-0.5797	Yes
80	CYLD	6590079	17073	-0.438	-0.5729	Yes
81	CHUK	7050736	17374	-0.567	-0.5766	Yes
82	TRAF6	4810292 6200132	17407	-0.581	-0.5655	Yes
83	MAPK14	5290731	17410	-0.583	-0.5528	Yes
84	MAP2K6	1230056 2940204	17445	-0.603	-0.5413	Yes
85	NFKBIA	1570152	17455	-0.610	-0.5284	Yes
86	STAT2	3780519	17559	-0.664	-0.5193	Yes
87	IL6ST	5890047	17628	-0.698	-0.5076	Yes
88	BCL10	2360397	17734	-0.764	-0.4965	Yes
89	GATA3	6130068	17815	-0.824	-0.4827	Yes
90	MAP3K14	5890435	17867	-0.866	-0.4664	Yes
91	SPHK2	2030487 4120670 4850114	17916	-0.910	-0.4489	Yes
92	SOCS1	730139	17976	-0.958	-0.4310	Yes
93	IL2RG	4120273	17992	-0.973	-0.4104	Yes
94	STAT1	6510204 6590553	18024	-1.010	-0.3899	Yes
95	STAT3	460040 3710341	18039	-1.029	-0.3680	Yes
96	CD3E	3800056	18080	-1.072	-0.3465	Yes
97	CD4	1090010	18267	-1.396	-0.3258	Yes
98	MAPK9	2060273 3780209 4070397	18410	-1.795	-0.2940	Yes
99	CD3G	2680288	18433	-1.872	-0.2540	Yes
100	CD8B	1940411 2570035	18445	-1.897	-0.2128	Yes
101	CD247	3800725 5720136	18457	-1.964	-0.1702	Yes
102	TNFAIP3	2900142	18460	-1.987	-0.1266	Yes
103	CD28	1400739 4210093	18471	-2.047	-0.0820	Yes
104	TNFRSF1A	1090390 6520735	18609	-4.080	0.0004	Yes